Studies of essential fatty acid metabolism in collagen disease (second report)
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چکیده
منابع مشابه
Essential fatty acid metabolism and its modification in atopic eczema.
Research from the 1930s to the 1950s established that a deficit of n-6 essential fatty acids (EFAs) leads to an inflammatory skin condition in both animals and humans. In a common inherited skin condition, atopic dermatitis (eczema), there was evidence of low blood EFA concentrations and of a therapeutic response to exceptionally high doses of linoleic acid. More recently, it has been establish...
متن کاملMetabolism of Essential Fatty Acids
The fat deficiency disease in the rat (I), dog (2), and chick (3) is characterized in part by sharply increased concentrations of one or more trienoic acids in the tissues, as indicated by alkali isomerization analyses. Indeed, the increase in conjugatable triene in the mitochondrial fatty acids may be the first noticeable symptom of the onset of fat deficiency (4). The major triene component o...
متن کاملDysregulation of hepatic fatty acid metabolism in chronic kidney disease.
BACKGROUND Chronic kidney disease (CKD) results in hypertriglyceridemia which is largely due to impaired clearance of triglyceride-rich lipoproteins occasioned by downregulation of lipoprotein lipase and very low-density lipoprotein (LDL) receptor in the skeletal muscle and adipose tissue and of hepatic lipase and LDL receptor-related protein in the liver. However, data on the effect of CKD on ...
متن کاملFatty acid metabolism studies of human epidermal cell cultures.
Adult human epidermal keratinocytes grow rapidly in medium that is essential fatty acid (EFA)-deficient. In this medium they exhibit decreased amounts of the fatty acids, 18:2, 20:3, 20:4, and contain increased amounts of monounsaturated fatty acids. [14C]- and [3H]acetate and radiolabeled fatty acids, 16:0, 18:2, and 20:4 were used to study the fatty acid metabolism of these cells. Label from ...
متن کاملMyocardial fatty acid metabolism in health and disease.
There is a constant high demand for energy to sustain the continuous contractile activity of the heart, which is met primarily by the beta-oxidation of long-chain fatty acids. The control of fatty acid beta-oxidation is complex and is aimed at ensuring that the supply and oxidation of the fatty acids is sufficient to meet the energy demands of the heart. The metabolism of fatty acids via beta-o...
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ژورنال
عنوان ژورنال: Ensho
سال: 1981
ISSN: 0389-4290,1884-4006
DOI: 10.2492/jsir1981.1.5_703